About Us

How it all started

Stand Up 2 Cancer (SU2C) and the St. Baldrick’s Foundation funded the first Pediatric Cancer Dream Team (PCDT) to create new therapies for high-risk childhood cancers. Led by Dr. John Maris and Dr. Crystal Mackall, the team focused on developing new classes of therapeutics to improve treatments for children using new antibodies, antibody-drug combinations and CAR T-cell therapies. From July 2013 to June 2018, the team opened 25 clinical trials and treated 688 pediatric cancer patients.


Where We Are Now

The synergies and successes of the first pediatric cancer dream team created a momentum that was too large to stop. The entire team wanted to continue to work together to push forward on the advances made in the first phase of the project. The St. Baldrick’s Foundation stepped forward to jointly fund the second phase of the Pediatric Cancer Dream Team. With funding from the St. Baldrick’s Foundation and the partner Institutions, the second phase of the Pediatric Cancer Dream Team involves 10 Institutions across the United States and Canada and includes oncologists, early career researchers, patient advocates, and many others.


This current St. Baldrick’s – SU2C Pediatric Cancer Dream Team has now treated over 1100 children on new immunotherapy clinical trials. The network has grown to include major new research initiatives under the umbrella of the Beau Biden Cancer Moonshot initiative within the Pediatric Immunotherapy Discovery and Development Network.


In April 2021, the PCDT was awarded the American Association for Cancer Research (AACR) Team Science Award, recognizing the significant contribution the PCDT has made to the pediatric cancer research community.

Stories about the PCDT:

CHOP Cancer Researchers Win 2021 AACR Team Science Award

Dream Teams: St. Baldrick's Foundation-SU2C Pediatric Cancer Dream Team: Immunogenomics to Create New Therapies for High-Risk Childhood Cancers.

Stand Up to Cancer: SU2C–St. Baldrick’s Foundation Pediatric Cancer Dream Team: Immunogenomics to Create New Therapies for High-Risk Childhood Cancers

St. Baldrick's Foundation: Pediatric Cancer Dream Team Works Toward More Breakthroughs