Children's Hospital of Philadelphia
Jennifer Baldi - Program Manager
john maris, md - leader
Dr. John Maris is Giulio D’Angio Professor of Pediatrics in the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia. He is a physician-scientist who has focused for over three decades on the childhood cancer neuroblastoma with the dual goals of improving patient outcomes and also using the disease as a model to understand cancer in general.. His group has discovered all of the known neuroblastoma susceptibility genes and his group has also identified many of the oncogenic drivers of the disease. Dr. Maris has steadfastly sought to translate these discoveries to the clinic using precision medicine approaches and more recently by co-leading a multi-institutional St. Baldrick’s Foundation- Stand Up to Cancer Pediatric Cancer Dream Team project to bring the fields of genomics and immunology together to combat childhood cancers, and more recently a Beau Biden Moonshot Center Award to extend this rapidly evolving area of research. Dr. Maris is an internationally recognized practicing pediatric oncologist who cares for children with refractory neuroblastoma from around the world, typically in the context of early phase clinical trials. Dr. Maris has been continuously funded by the National Institutes of Health and many other funding bodies. He currently holds a National Cancer Institute Outstanding Investigator Award and has received several prestigious awards including election into the American Society of Clinical Investigation, the Oski award for outstanding pediatric oncologists, and the Berwick award at Penn for melding basic and clinical teaching, and the William Osler Patient Oriented Research Award at Penn.
Sharon diskin, phd - investigator
Stephan Grupp, md phd - Investigator
Stephan Grupp, MD PhD, is the Chief of the Cellular Therapy and Transplant Section, Director of the Cancer Immunotherapy Program, and Medical Director of The Cell and Gene Therapy Lab at the Children’s Hospital of Philadelphia (CHOP), as well as the Yetta Dietch Novotny Professor of Pediatrics at the University of Pennsylvania Perelman School of Medicine. Dr. Grupp graduated from the University of Cincinnati after completing the MD/PhD program with a PhD in Immunology.
Yael mosse, md - investigator
Sarah tasian, md - investigator
andrei thomas-tikhoneko, phd - investigator
Kristopher Bosse, md - Young investigator
Jessica Foster, md - young investigator
shannon maude, md phd - young investigator
mark yarmarkovich, phd - young investigator
Amber Weiner, phd - young investigator
Amber K. Weiner, PhD is a postdoctoral fellow at the Children’s Hospital of Philadelphia in the Division of Oncology and Center for Childhood Cancer Research. She graduated from Arcadia University with a Bachelor’s in Biology and completed her PhD in Genomics and Computational Biology at the University of Pennsylvania Perelman School of Medicine. She is a member of the St. Baldrick’s Foundation – Stand Up 2 Cancer Pediatric Cancer Dream Team (SBF-SU2C) and Pediatric Immunotherapy Discovery and Development Network (PI-DDN). During her PhD, she was co-advised by Drs. Sharon Diskin, John Maris and Benjamin Garcia. Her interdisciplinary thesis project involves integrating mass spectrometry based proteomics and RNA-sequencing/microarray data to discover novel immunotherapeutic targets for validation in preparation for preclinical testing and clinical trials. We have prioritized DLK1, an epigenetically regulation protein and showed potent/specific activity of a DLK1 directed antibody drug conjugate. She has also focused on developing shiny applications for mass spectrometry data analysis (GiaPronto) and data release to the scientific community (PIONEER). She is also a member of the SBF-SU2C advocacy committee where she has worked to advance childhood cancer research through young investigator and advocate collaboration.
Bruce Pawel, MD PhD
David Barrett, MD PhD
Hamid Bassiri, MD PhD
Mike Hogarty, MD
Mariarita Santi-Vicini, MD PhD
Yimei Li, PhD